Serious Neurologic Events after Epidural Glucocorticoid Injection — The FDA’s Risk Assessment

From the New England Journal of Medicine: At times, the Food and Drug Administration (FDA) must grapple with safety concerns related to off-label uses of FDA approved medications. Over the past several years, we have sought to understand the risk of serious neurologic events that occur after the epidural injection of glucocorticoids (corticosteroids) — a procedure that is commonly performed …

Epidural Steroid Injection Paralyzes Woman at Denver ASC

The case of a 60-year-old woman paralyzed from the waist down after receiving an epidural injection of Kenalog at a Denver surgical center has reignited the debate over the off label use of corticosteroids. Epidural steroid injections are the most common procedure doctors perform for low back pain — done nearly 9 million times a year. But the FDA has …